Active Hexose Correlated Compound
En Español (Spanish Version)
Alternate Names/Related Terms:
Principal Proposed Uses:
Other Proposed Uses:
In Japan, various mushrooms and tree fungi have a long history of medicinal use. Active Hexose Correlated Compound (AHCC) is a proprietary compound made from the mycelia (vegetative portion) of various mushrooms in the general family of basidiomycete. The exact composition of the mushrooms, as well as the method used to prepare them, are considered a trade secret. AHCC has been developed in Japan for use in treatment of cancer. For related treatments, see the articles on Maitake, Shiitaki, and Reishi.
AHCC is primarily advocated as an aid to cancer treatment, said to improve survival in people undergoing treatment for liver cancer and other forms of cancer. However, current evidence that it works is far too preliminary to be taken as meaningful, consisting as it does only ofanimal studiesand a few entirely inadequate human trials.1-4 Only double-blind studies can actually prove a treatment effective, and none have yet been performed on AHCC. (For information on why this type of study is essential, see Why Does This Database Depend on Double-Blind Studies?)
Other proposed uses of AHCC have even weaker supporting evidence. These include decreasing chemotherapy side effects,5reducing cancer risk,6treating inflammatory bowel disease,7 and generally enhancing immune function.8-13
Last reviewedSeptember 2014by EBSCO CAM Review Board
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