Wolfberry, the berry of the Lycium chinensis plant, have a long history of use in traditional Chinese herbal medicine. Chinese herbal medicine is part of an ancient and complex medical system that analyzes the effects of treatments in terms of their effects on the "energy" of various organs. Within this system, lycium berry has the following effects: nourishing liver and kidneys, moistening the lungs and supplementing the yin. (For more information on these pre-scientific medical concepts, see the full Traditional Chinese Herbal Medicine article.) Typical uses based on these actions include life extension and treatment of dry skin, dizziness, diminished sexual desire, low back pain and chronic dry cough.

The Tibetan Goji berry is closely related to Chinese lycium.

Wolfberry is a nutritious food, containing relatively high levels of numerous vitamins and minerals. However, other proposed uses of wolfberry have no meaningful supporting evidence.

For example, while wolfberry is widely marketed as a life extension aid, there is no scientific evidence that it offers this benefit. In fact, even within the framework of traditional Chinese herbal medicine, the herb's action is far more complex and it would not be expected to prolong life per se. Much the same can said regarding the proposed uses of wolfberry to enhancemale or female sexual function.

Weak evidence from test tube studies, far too preliminary to rely upon at all, hints at potential liver protective,1-3anti- Alzheimer's Disease,4anti-cancer,5 and cholesterol - and blood-sugar -lowering 6 effects.