Rhabdomyolysis occurs when skeletal muscles are damaged and release myoglobin into the bloodstream. Myoglobin is an iron-containing pigment that can cause severe damage to the kidneys.
Rhabdomyolysis results from any condition that causes significant muscle damage. These include:
- Excessive muscle activity
- Certain muscle diseases
- Severe muscle injuries, such as a crush injury
- Overuse of alcohol or illicit drugs
- Uncontrolled seizure disorder
- Contact with an electrical current
- Toxins, such as snake or spider venom
- Extensive surgical procedures using large, muscle-dividing incisions—rare
Last reviewedJuly 2013by Adrienne Carmack, MD; Michael Woods, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.