Pronounced: Sclare-oh-DER-mahEn Español (Spanish Version) More InDepth Information on This Condition
Scleroderma is a rare disease of the connective tissue. It can cause the tissue in skin, joints, and internal organs to thicken and stiffen. There are three major forms of the disease:
- Localized scleroderma (can be morphea or linea)—Usually affects only the skin in isolated parts of the body. This form is less serious.
- Systemic sclerosis—Affects widespread areas of skin and/or internal organs, most often the lungs. Certain categories of this form of scleroderma are more serious and can be fatal.
- Overlap syndrome—May involve features of scleroderma and features of other autoimmune syndromes.
Last reviewedMay 2014by Michael Woods, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.