Scutellaria baicalensis, also called Chinese skullcap, is a member of the mint family and has long been used in traditional Chinese herbal medicine. Chinese skullcap has been incorporated in herbal formulas designed to treat such widely varying conditions as cancer, liver disease, allergies, skin conditions, and epilepsy. The root is the part used medicinally.

Note: Chinese skullcap is substantially different from American skullcap ( Scutellaria lateriflora).

The root of Chinese scullcap contains the flavonoids baicalin, wogonin, and baicalein, and most studies have involved these substances rather than the whole herb.

Highly preliminary evidence suggest that baicalin can enhance the activity of antibiotics against antibiotic-resistant staph bacteria.1-3 Other highly preliminary evidence suggests that baicalin, wogonin, and baicalein may have anti-cancer,4-8anti-inflammatory,9,10liver-protective,11anti-anxiety,12 and antihypertensive effects.13 However, for none of these uses does the evidence approach the level necessary to truly establish a treatment as effective.

Research involving combination herbal therapies containing Chinese skullcap are discussed in the Traditional Chinese Herbal Medicine article.