In its early phases, chronic kidney disease usually doesn’t cause symptoms. However, as the condition progresses to the end-stage renal disease stage, it can cause a number of symptoms, including:

  • Feeling weak or tired
  • Trouble sleeping
  • Swelling of feet and ankles
  • Poor appetite
  • Needing to urinate more often, especially at night
  • Muscle cramping at night
  • Nausea
  • Itching
  • Shortness of breath
  • Metallic taste in mouth
  • Chest pain
  • Confusion
  • Hiccups
  • Irritability
  • Difficulty concentrating
  • Reduced interest in sex
  • Menstrual irregularities
  • Numbness and tingling in hands and feet