Pronounced: am’i-loy-dō’sisEn Español (Spanish Version)
Amyloidosis is a group of rare diseases. It involves deposits of a protein called amyloid. These proteins build up in body tissues and organs. There are three major forms:
- Primary amyloidosis—found in the heart, lungs, skin, tongue, thyroid gland, intestines, liver, kidneys, and blood vessels
- Secondary amyloidosis—found in the spleen, liver, kidneys, adrenal glands, and lymph nodes
- Hereditary amyloidosis—found in the nerves, heart, blood vessels, and kidneys
The causes of amyloidosis vary in its different forms.
- Primary amyloidosis—caused by the deposit of antibody fragments; associated with bone marrow disorders such as multiple myeloma
- Secondary amyloidosis—develops in response to chronic infection or inflammatory disease
- Hereditary amyloidosis—caused by mutations of amyloid in the blood
Last reviewedAugust 2013by Igor Puzanov, MD; Michael Woods, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.