Pronounced: ne-frop-a-theeEn Español (Spanish Version)
IgA nephropathy is a disorder of the kidney. It may start with minor changes in the kidneys, but it can lead to chronic kidney disease or kidney failure.
Anatomy of the Kidney
Copyright © Nucleus Medical Media, Inc.
IgA nephropathy is caused by a buildup of the IgA protein in the kidneys. IgA proteins help the body fight infections. There are more of these proteins when you have an infection like the cold or flu.
The protein buildup can damage the filters of the kidneys. These filters are needed to clean the blood as it passes through. If the filters are damaged, then the kidneys are not able to clean the blood. Minor damage to the filters will not cause any changes. Major damage will worsen your health. IgA nephropathy can also cause some blood and protein to leak into the urine.
Genetics may play a role in the buildup of IgA proteins in the kidney.
Last reviewedMay 2014by Adrienne Carmack, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.